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  1. Substance P - Wikipedia

    Substance P and other sensory neuropeptides can be released from the peripheral terminals of sensory nerve fibers in the skin, muscle, and joints. It is proposed that this release is involved …

  2. Biochemistry, Substance P - StatPearls - NCBI Bookshelf

    Jul 30, 2023 · Substance P (SP) is an 11-amino acid-long neuropeptide expressed by the central nervous system (CNS), the peripheral nervous system, and immune cells. SP is a member of …

  3. Substance P - an overview | ScienceDirect Topics

    Substance P is a neurotransmitter present in the brain and spinal cord, where it is known to be involved in pain signaling. In the PAG/DR, substance P is generally uniformly present …

  4. What Is Substance P and What Is Its Role in the Body ...

    Jul 28, 2025 · Substance P is a neuropeptide, a signaling molecule composed of amino acids, found throughout the body. It is particularly concentrated within the nervous system, including …

  5. Substance P Definition - Intro to Brain and Behavior Key Term ...

    Substance P is released by nociceptive neurons in response to painful stimuli, amplifying the pain signal sent to the brain. It is involved in several physiological processes beyond pain, including …

  6. Substance P - Exploring Peptides

    Substance P is a neuropeptide that plays a crucial role in the transmission of pain signals and is involved in various physiological processes, including inflammation, mood regulation, and …

  7. The Role of Substance P in the Regulation of Bone and ...

    Feb 28, 2020 · Substance P (SP) is a neuropeptide that is released from sensory nerve endings and is widely present in nerve fibers. It acts on bones and related tissues by binding to …

  8. Substance P: Important Neurotransmiter in Pain Perception and Inflammatory Processes Sarah Holland* Department of Neuroscience Excellence, Louisiana State University, USA

  9. Substance P: Functions in Pain, Gut Health, & Immunity

    Jul 22, 2025 · Substance P is a neuropeptide, a small protein-like molecule that functions as a chemical messenger for nerve cells. It is a member of the tachykinin family of peptides, …

  10. Substance P | SpringerLink

    Substance P is an 11 amino acid neuropeptide that is a member of the tachykinin neuropeptide family and funtctions as a neurotransmitter and neuromodulator. It is present in both primary …