BRCA Gene Changes: Cancer Risk and Genetic Testing
A fact sheet about the BRCA1 and BRCA2 genes, what to do if a person tests positive for alterations in one of these genes, and consequences of genetic testing.
BRCA1 and BRCA2 (PDQ®) - NCI - National Cancer Institute
Evidence-based, expert-reviewed summary about the BRCA1 and BRCA2 genes and hereditary breast and ovarian cancer. This summary also contains information about the cancer risks …
MRI, Surgery Reduce Cancer Deaths in Women with BRCA Changes
Apr 15, 2024 · For women with inherited harmful changes in BRCA genes, MRI surveillance and salpingo-oophorectomy can modestly reduce their risk of dying from breast and ovarian …
Discovery – BRCA Connection to Breast and Ovarian Cancer
NCI-funded research helped identify inherited BRCA1 and BRCA2 genetic mutations and their connection to breast and ovarian cancer. From this research, a screening test was also …
Genetic Testing Fact Sheet - NCI - National Cancer Institute
A fact sheet about genetic testing for inherited cancer risk. Includes who should consider testing, and how to understand test results.
Surgery to Reduce the Risk of Breast Cancer
Dec 2, 2025 · A fact sheet that describes mastectomy and salpingo-oophorectomy, two surgeries that may be used to reduce the risks of breast and ovarian cancers in people, and nonsurgical …
Breast Cancer Risk Assessment Tool: Online Calculator - NCI
An interactive calculator that estimates a patient's risk of developing breast cancer. Also known as The Gail Model. Designed by scientists at the National Cancer Institute and the NSABP.
Hoja informativa sobre los cambios en el gen BRCA y las pruebas …
Hoja informativa sobre los genes BRCA1 y BRCA2, qué hacer si la prueba de una persona indica que tiene cambios en uno de estos genes y las consecuencias de las pruebas genéticas.
Olaparib Approved for Breast Cancers with BRCA Gene Mutations
Jan 29, 2018 · The Food and Drug Administration has approved olaparib (Lynparza®) to treat metastatic breast cancers that have inherited mutations in the BRCA1 or BRCA2 genes as …
PALB2 and Associated Cancer Risks (PDQ®) - NCI
Feb 14, 2025 · Evidence-based, expert-reviewed summary about the PALB2 gene, the cancer risks associated with PALB2, screening, risk-reduction, treatment, and prognosis.