Higher levels of CD4-positive naïve T cells in patients receiving CAR T-cell therapy for multiple myeloma are associated with ...
CAR-T therapy is a major advance in cancer care, but high costs and centralized global manufacturing limit access.
Data presented at ASH 2025 suggest earlier-line use of cilta-cel leads to better outcomes in multiple myeloma because patients have fitter immune systems and less exhausted T cells, improving CAR T ...
The use of base editing to generate universal off-the-shelf CAR T cells induced durable remissions -- up to 36 months in one ...
CAR-T cell therapy provides long, treatment-free remissions for relapsed multiple myeloma, using genetically modified T cells ...
At ASH 2025, investigators reported early results from the first-in-human phase 1 inMMyCAR study evaluating KLN-1010, an ...
Cell-based immunotherapies have transformed cancer treatment, yet their widespread use remains constrained by safety risks, ...
Autolus Therapeutics is working with Cellares to assess automated CAR T manufacturing to support rising demand for its ...
Cold Spring Harbor Laboratory researchers reveal a groundbreaking approach using CAR T-cell therapy to rejuvenate aging ...
Next-generation automation is closing the gap between curative science and real-world demand, enabling faster development, ...
Researchers have discovered a way to help aging intestines heal themselves using CAR T-cell therapy, targeting senescent ...
Nona Biosciences ("Nona"), a global biotechnology company advancing biologics discovery through innovative technology ...