Northwestern Medicine scientists have discovered how calcium signaling channels in microglia—the primary immune cells of the brain—regulate neuroinflammation and promote the development of behaviors ...

Gut dysbiosis caused by a high-fat diet can allow bacteria to move from the gut to the brain in mice, according to a new study by David Weiss and Arash Grakoui from Emory University, U.S., and ...

Stimulant medications and non-stimulant medications affect brain chemistry through different mechanisms”— Dr. Stanford ...

NAEs are lipid-based endogenous signaling molecules that are produced by combining long-chain fatty acids with ethanolamine. Collectively, NAEs include both endocannabinoids and structurally related ...

Researchers identify PV neurons in the prefrontal cortex as the gatekeepers of drug addiction relapse, offering a new target for precision treatment.

You will be redirected to our submission process. This Research Topic is part of the Mechanisms and Novel Therapeutic Targets and Approaches for Mitochondrial Dysfunction in Neurological and ...

Researchers have discovered that mutations in the FOXJ3 gene act as a "master switch" failure, disrupting how the brain builds its layers and leading to FCD, a primary cause of drug-resistant epilepsy ...

A new genomic study isolates a mania-specific factor that explains over 80% of bipolar disorder’s genetic risk, tying it to calcium-channel signaling and risk‑taking traits.