AZoLifeSciences on MSN
Deep learning–based codon optimization framework boosts protein expression in E coli
By combining Transformer-based sequence modeling with a novel conditional probability strategy, the approach overcomes ...
Discover how early CMC, process optimization, and formulation strategy drive scalable, commercially viable drugs.
A virus relies on the host's translation machinery to replicate itself and become infectious. Translation efficiency ...
This study offers important insight into the pathogenic basis of intragenic frameshift deletions in the carboxy-terminal domain of MECP2, which account for some Rett syndrome cases, yet similar ...
Abstract: Co-optimizing mRNA sequences for both codon optimality and secondary structure is crucial for producing stable and efficacious mRNA therapeutics. Codon optimization, which adjusts nucleotide ...
The way people search for information has changed, and business leaders need to move fast to keep up. Fewer potential clients are typing in keywords and clicking on links. Instead, they’re getting ...
Jake brings two decades of experience with him, having covered major industry events, breaking news, one-on-one interviews, and more. When he's not playing World of Warcraft, he's usually on the hunt ...
Abstract: The concept of codon optimization is one that has recently been introduced to overcome the potential functional problems of DNA introduced into foreign hosts. We present a dynamic ...
Good news…SEO is alive and well. And the bad news? Traditional SEO approaches are no longer sufficient in today's AI-driven search landscape. Search strategy has ...
Customizable expression systems are the future of bioprocessing, making cell-line development (CLD) the vital basis of production success. Artificial intelligence (AI) and machine learning (ML) will ...
Some results have been hidden because they may be inaccessible to you
Show inaccessible results