Proteins are far more than nutrients we track on a food label. Present in every cell of our bodies, they work like nature's molecular machines. They walk, stretch, bend, and flex to do their jobs, ...

University of Virginia School of Medicine scientists have developed a bold new approach to drug development and discovery that could dramatically accelerate the creation of new medicines. UVA's ...

Researchers have identified a previously unknown bacterial protein, the structure of which is being used in the design of protein nanoparticles for the targeted delivery of anticancer drugs to tumors.

For all the excitement surrounding AlphaFold and the surge of AI‑driven protein design tools, one fact often goes unexamined: nearly every model is trained on databases of known proteins. These ...

The number of known proteins is infinitely small in comparison to the universe of possible proteins which could in theory be realized. Yet these known proteins are the only major training ground for ...

SYNTHBODY(TM) introduces a new class of "smart drugs": protein therapeutics with built-in, multi-layered logic gates that actively change how they behave based on what they encounter in the body, a ...

A domestic research team, together with the lab of David Baker, the 2024 Nobel Prize in chemistry laureate and a professor at the University of Washington, used artificial intelligence (AI) to design ...

Identifying small-molecule binders for complex biological targets remains a major challenge in early drug discovery, particularly when working with membrane proteins or large protein complexes. Mass ...