Jacqueline M. McMillan, Elizabeth Aitken and Jayna M. Holroyd-Leduc The appropriate assessment and management of chronic insomnia is crucial. Insomnia affects quality of life and has been shown to be ...
In this issue of CMAJ, Dzakpasu and colleagues1 show that hypertensive disorders of pregnancy have increased 40% over the last decade in Canada, although early recognition and treatment have curtailed ...
Background: Fragility fractures are a major health concern for older adults and can result in disability, admission to hospital and long-term care, and reduced quality of life. This Canadian Task ...
Smoking marijuana can increase clearance of some drugs Smoked marijuana increases the clearance of theophylline 40%. 1 Similar findings would be expected for other drugs metabolized by CYP1A2, such as ...
Iron deficiency and iron deficiency anemia are common during pregnancy and are associated with adverse outcomes Prenatal iron deficiency occurs in more than 30% of pregnancies in Canada. 1 It has been ...
Major hemorrhage is a challenging clinical problem that can occur with traumatic injury, postpartum hemorrhage, major surgery and gastrointestinal bleeding. A massive hemorrhage protocol (MHP) should ...
Background: The drug toxicity crisis continues to accelerate across Canada, with rapid increases in opioid-related harms following the onset of the COVID-19 pandemic. We sought to describe trends in ...
Conversion therapy continues to occur in both regulated and unrelated settings in Canada, prompting federal, provincial and territorial, and municipal governments to have debated and enacted dozens of ...
Nonnutritive sweeteners and cardiometabolic health: a systematic review and meta-analysis of randomized controlled trials and prospective cohort studies ...
Pressurized metered-dose (pMDI) inhalers are an important contributor to greenhouse gas emissions Hydrofluorocarbon propellants in pMDIs are responsible for roughly 0.03% of yearly global greenhouse ...
Croup develops in more than 80 000 Canadian children each year, making it the second most common cause of respiratory distress in the first decade of life. [1] [1], [2] [2] It affects boys more than ...
Bupropion abuse is a growing public health problem Although bupropion shares some structural and pharmacologic properties with amphetamine, early research suggested the drug did not produce any ...
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