In 1927, J.B.S. Haldane reasoned that the probability of fixation of new beneficial alleles is twice their fitness effect. This result, later generalized by M. Kimura, has since become the cornerstone ...

A new diagnostic tool can effectively discriminate different rheumatologic conditions and could potentially aid in the diagnosis of early inflammatory arthritis. The algorithm — called Genetic ...

The field of medical genetics is swiftly evolving. It's a period of rapid scientific discovery, new technologies and subsequent translation into medical practice, public policy and public health. But ...

To the Editor: I am a medical geneticist whose active practice at the end of my career is devoted almost exclusively to determining the genetic or mutational basis for established, and usually ...