IN the skin of mice painted with chemical carcinogens a remarkable accumulation of mast cells is usually observed in the altered dermis. Cramer and Simpson 1 first observed that the accumulating mast ...

Mast cell stabilizers appear to have the potential to control IRRs and possibly allow for the safe reintroduction of agalsidase in patients with Fabry disease who previously received enzyme ...

Mast cell precursor cells do not just cause an increase in mature mast cells during inflammation, they also play an active role in diseases like asthma, according to a new study. Mast cell precursor ...

Known for their role in allergic reactions, mast cells have long been recognised as key players in our immune system. When they encounter allergens, they release chemicals that trigger typical allergy ...

This scanning electron microscopy image captures the moment where degranulating mast cells (pseudo-colored in sepia) attract and start to incorporate living neutrophils (pseudo-colored in cyan), ...

Although many topical or systemic antibiotics exist to treat acne vulgaris, the common inflammatory skin disease is not fully treatable. A new article published in The Journal of Clinical and ...

A CURIOUS feature of carcinogenesis in the skin of the mouse is the intense mast-cell reaction which gradually develops in the dermis immediately under the painted hyperplastic epidermis. Cramer and ...

In a recent study published in Nature, researchers used a mouse model to show that mast cells and immunoglobulin E (IgE) are the key orchestrators of antigen-specific avoidance, a behavioral ...

Scientists at Zhejiang University have found a way to turn allergy-causing cells in the body into cancer-fighting agents, offering a new targeted approach that combines immune system activation with ...

Nurse Amy Lochtie was in a meeting about infection control the first time she went into anaphylaxis — a severe reaction, usually related to an allergy, which can be life-threatening. But in her case, ...