Oregon Health & Science University has a leading role in a new database designed to track the normal expression of genes in organs and tissues from prenatal development through adulthood. Researchers ...

Different variants of a gene, known as isoforms, can be transcribed and translated at varying levels within a cell or tissue. These isoforms are commonly a result of alternative splicing, which ...

Mitochondrial enzymatic activity and mtDNA density measures display low between-tissue correlations across 22 tissues from 27 mice. A long-standing assumption is that mitochondrial energy capacity is ...

A Yale research team has created a new imaging technique that reveals the hidden connections between aging, disease, and genetic activity in human cells. Using a novel machine learning approach, the ...

A new research paper was published in Aging (Aging-US) on January 3, 2025, in Volume 17, Issue 1, titled "Characterization of DNA methylation clock algorithms applied to diverse tissue types." ...

“Our results suggest that forensic applications of DNAm clocks using non-blood tissue types will provide age estimates that are not as accurate as predictions based on blood, especially if using ...