The study of experimental evolution in Escherichia coli has provided unprecedented insights into the mechanisms of adaptive mutations, elucidating how populations diverge and optimise their fitness ...
In real life, mutants can arise when their DNA changes to give them an advantage over the rest of the population. A team from ...
A groundbreaking study published in this week’s issue of PNAS by scientists from Israel and Ghana shows that an evolutionarily significant mutation in the human APOL1 gene arises not randomly but more ...
Mitochondria are known as the body’s “energy factories,” and their function is essential for life. Inside mitochondria, a set of complexes called the oxidative phosphorylation (OxPhos) system ...
Researchers published a new study, “Ongoing chromothripsis underpins osteosarcoma genome complexity and clonal evolution,” in Cell that they say solves the mystery of what drives the genomic ...
The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20100 possible variants—more combinations than atoms in the observable universe.
A major evolutionary theory says most genetic changes don’t really matter, but new evidence suggests that’s not true. Researchers found that helpful mutations happen surprisingly often. The twist is ...
This year’s Sjöberg Prize of one million US dollars is awarded to a British cancer researcher who has provided fundamental knowledge about evolution in tumours. Charles Swanton, at the Francis Crick ...
In 1990, I finished my PhD on primate evolution and went to my postdoc in Davis, California, USA. It was meant to be on fruit fly ...
Groundbreaking research shows that as men age, harmful genetic mutations in sperm become more common—not just from random chance, but because some are naturally favored. Advanced sequencing revealed ...
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MULTI-evolve accelerates protein engineering with machine learning
The search space for protein engineering grows exponentially with complexity. A protein of just 100 amino acids has 20^100 possible variants-more combinations than atoms in the observable universe.
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