One of the most widely accepted models for how cells remember their identity may be incorrect. This is shown in a new study ...
Researchers have developed a human intestinal cell model that closely mimics the structure and function of the human gut, enabling more precise prediction of drug-induced gastrointestinal toxicity ...
A remarkably small bacterium containing fewer than 500 genes serves as the basis for one of the most detailed digital life reconstructions ever created. Using computer technology, scientists have ...
By simulating the life cycle of a minimal bacterial cell—from DNA replication to protein translation to metabolism and cell ...
To model bacterial life, Thornburg and his colleagues turned to one of its simplest examples: a bacterial cell with a ...
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Intestine-mimicking cell model accurately predicts drug toxicity
A cell model that replicates the structure and function of the human intestine has been developed, creating an evaluation platform capable of more accurately predicting adverse effects of new drugs.
Researchers recently developed a bone marrow model to study how the body generates cells. Interestingly, this model is the first of its kind to be developed entirely from human cells. Not only can ...
Typically, bone marrow research relies heavily on animal models and oversimplified cell cultures in the laboratory. Now, researchers from the Department of Biomedicine at the University of Basel and ...
Researchers at Helmholtz Munich and the Technical University of Munich (TUM) have developed Nicheformer, the first large-scale foundation model that integrates single-cell analysis with spatial ...
Every cell in a body contains the same genetic sequence, yet each cell expresses only a subset of those genes. These cell-specific gene expression patterns, which ensure that a brain cell is different ...
The human cell is a miserable thing to study. Tens of trillions of them exist in the body, forming an enormous and intricate network that governs every disease and metabolic process. Each cell in that ...
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