Traditionally, scientists have used 2D cell cultures as in vitro models in drug screening studies due to their simplicity and scalability. However, 2D cell models do not recapitulate the complexity of ...

The overarching experimental design is depicted in Figure . On day 1, each cell type was seeded on uniquely colored cell carriers (Huh7 on white, THP1 on red, and LX2 on blue). On day 2, the Huh7 ...

Most potential oncology drugs fail during the drug development pipeline, even when there has been promising data for their efficacy during the in vitro stage. This makes it vital to identify in vitro ...

This article is based on a poster originally authored by D. Cole and N. Bevan. 3D models, including spheroids and organoids, are increasingly used to investigate disease and development. Developing, ...

In this compendium of applications, Sartorius demonstrate the power and flexibility of the Incucyte® Live-Cell Analysis System for the study of spheroids and organoids in foundational research, ...

Researchers translated experimental data into Minecraft files to recreate 3D images in a more accessible setting. My group studies the minimum requirements for cells to live. As part of one project, ...

Researchers developed a microfluidic chip with 3D-printed microstructures that moves droplets precisely, captures cells efficiently, and quickly forms cell spheroids for improved lab-grown tissue ...

Tick-borne encephalitis virus, known as TBEV, hijacks the internal membrane machinery of host cells to build hidden factories ...

Growing cells in three dimensions is critical for studying how tissues behave in the body, yet most laboratory platforms remain either too simple or too complex to use widely. Researchers now present ...